Titels | Prof. dr. |
Initials | P |
Main position | Hoogleraar UU |
Disciplines | Solid-state physics |
Biochemistry | |
Biophysics, clinical physics | |
Chair | Biomacromoleculaire Kristallografie |
Domain | Natural Sciences and Engineering |
Membership | Member |
Since | 2010 |
Member of Natural Sciences and Engineering | |
Employed by |
Universiteit Utrecht
Faculteit Bétawetenschappen Kruytgebouw Padualaan 8 3584 CH Utrecht tel. 030 253 3127 p.gros@uu.nl |
Personal website | |
Research/publications |
Piet Gros studies the molecular mechanisms of recognition and regulation that underlie biological processes. His major expertise is in structural biology of human plasma-proteins, cell-surface receptors and membrane proteins.
Regulation in cells and organisms is achieved by the interplay of proteins acting in concert to achieve a control over time and space. In many cases, the proteins involved are multi-domain proteins that function in large complexes. This enables a collective set of proteins to form a protein machinery that carries out elementary regulatory functions such as initiation, amplification, localization and inhibition.
His research goal is to reveal the mechanisms of tertiary and quaternary-structure induced activation in multi-domain proteins and multi-protein complexes that underlie the recognition and regulation processes.